Testosterone Undecanoate (Andriol) is a newly developed steroids, relatively speaking. Andriol is available orally with testosterone. Orally administered steroids have a basic compound alteration, and a little different indeed by nature. He mentions a considerable problem of hepatotoxicity. An application for an orally administered steroid exists since many patients fear needles or at least strongly hated. Researchers have sought to create a steroid that would not require 17-alpha-methyl alteration.
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The solution was to determine a new method for delivery whose liver was bypassed. This means that no change was needed to protect the steroids from being deactivated in the liver. This method of delivery is through lymphatic absorption. The only other available oral steroid is Methyltestosterone. When ingested with or after meals, it is reabsorbed by the cells of the lining of the small intestine through the lymphatic system. Thanks to this effect, Andriol avoids first-pass metabolism in the liver. Since a first-pass metabolism results in less of the agent being absorbed into the bloodstream, in addition Testosterone Undecanoate is absorbed. Some of the drug is then converted to DHT, which has a very strong affinity for androgen receptors. With this conversion of DHT, andriol does not convert to estrogen, at the same rate of many of its counterpart injectable testosterones, so the risks of estrogen-related side effects such as gynecologist and excess water retention are reduced when you use it. Thus, unlike its injectable counterparts, the removal of the HPTA is not quite so severe when using Andriol.
The result of not having such large estrogenic side effects as steroid mates is that Andriol's overall effectiveness is not as strong as its steroid mates. It has androgenic anabolic characteristics, but not to the same degree as many other steroids. Injectable contraceptives such as Testosterone Enanthate, Testosterone Cypionate, and Sustanon are all more potent Testosterone Undecanoate Agents. Daily doses of more than 200 mg per day should be consumed in order to make comparable gains out of andriol than with its injectable counterparts. As a consequence of this excess of Andriol, the HPTA would be removed to a greater degree and the trend for other side effects are more than fine, in which case a less expensive route would be to use an injectable steroid, either alone or in a stack.
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Andriol can be combined with most other steroids. Since water retention issues are relatively rare with andriol, the use of Testosterone Undecanoate while pooling or cutting are both possibilities. The use of ancillary drugs such as anti-estrogens such as nolvadex or clomid are not usually considered very important since estrogenic side effects are extremely rare because of andriol conversion to DHT. Estrogen related side effects normally stop when Andriol, the doses are decreased or if its use is interrupted. This is unlike the injectable form of testosterone, in which case the cycle can not be simply dropped. From 8 to 16 andriol cups can be used every day and are better distributed throughout the day. Three equal doses throughout the day with meals would be a good recommendation.
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Acne, water retention, high blood pressure, aromatization (which can cause gynecologist), and HPTA removal are all quite low with normal use of andriol. Liver toxicity is a side effect, but also usually low normal doses. At higher doses, all of these side effects may become more pronounced.